The second opinion

Got the results of the second opinion today. Results as follows:

Prostate, right base, needle core biopsies:
- Prostatic adenocarcinoma, Gleason grade 3 + 3 (score = 6), microfucus involving <5% of 1 / 2 cores (see comments)

A, B, C, E, F) Prostate, left base, left mid, left apex, right mid and right apex, needle core biopsies:
- High grade prostatic intraepithelial neoplasia, focal in right apex
- Acute inflammation, moderate in right mid
- Prostatic tissue with no evidence of malignancy (0 / 10 cores)

Comments: In contrast to the outside pathology report (with diagnosis of ASAP), we consider that there is enough number of malignant glands to confirm the diagnosis of a small focus of adenocarcinoma. Accompanying immunoperoxidase staining for HMWCK+p63 cocktail shows lack of basal cells in the malignant glands. Specimen from right mid shows moderate acute inflammation, which may explain, at least in part, a possible increase of serum PSA. A close follow-up, which may include mapping biopsies of the prostate, is recommended if clinically indicated. Dr. S. Lucia has reviewed this case and concurs.

Lots of big words! I immediately start to research all the big words on the web, in an attempt to tie down just what this doctorspeak is telling me. It's easy to get panicked about the various definitions on the web, but after speaking with both Dave and Jerry, I am reassured that we are moving on the right track. The second opinion has confirmed the cancer. The next step is a mapping biopsy to really nail down the scope of this "bug". We schedule for Aug with Dave.